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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '160a114984bfaa89dee062c035f425b8cbb71751d2aa1cf3fc8a18de4601de9a' 
  AND token = 'qIRgtnR0FDjeLw+DIgIuzjmPmT3m8UVJ7cVFyuP7Lt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}