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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c121dd75c8590f9c06849b3cf509c3ca195f8db730444de33e80a09c5c207453' 
  AND token = 'n/xYThb/SkzwQeOAuIBd5oswH2f25nfdZinQAmCQSYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}