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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4f2e80b23b7fb8acfcfc131c82cad8273f74146f83ec2ae82b2daf4f25a3a48' 
  AND token = 'ekXj6JBfYJ3lOhhB+9p/OWF8seV0FrAt+3kSndlVE9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}