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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5a641a3fc7ce3fe764afd98262a9a8a7df1a2a231e5c39431ddea32312d3e53' 
  AND token = 'IE+XZZ6yE0nSkz9e5zyIG0aqJms5gZza4UtOEVg+lc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}