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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c78a44e1120012869556f493bda8699a3752e6f87b91b5c17e9a251853fec65' 
  AND token = '8z8JFSrB+Axs9HH0FcJp7G3qhcsTDaQEojnlyzeyNMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}