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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161843b39dad6e0fc7e1ad17c00fe57f2756f726d488bd8861ff1263e65f89b4' 
  AND token = '/npaIDEF8yZ0CJUqYylads1AyzbUbQaPKsrFXxq8Pi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}