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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1ef465453f8d72bd8d1ffab18fe2f4c246a0c704f61d23567414d16ff9ccd9c' 
  AND token = 'Kx/OFZOt96Tl5yxFcZiWoqBDO5MqbOR/qNz0q4B8MIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}