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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c16a2862e83cbe682d848631c0baee46f28f0e6e47e38c07dadedcbfe95ad53' 
  AND token = 'xhQTgIFLTzz7FWBIoWMlrLfkqRj81+/GhTdvb0YFIeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}