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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6386648ab0d1e29b434f207bf010e5411e3f14c880cfe6f52fe665b123471553' 
  AND token = 'MYp/zwh57KEpT0BGRdFD4yXmZJxkokCy8990rpEykJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}