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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb49ce322aa7723ca8f9f09b9f34a22d403d17c332cf340a939cb72be6a9afcd' 
  AND token = '9ax9eLomgAJu9EXAVo2AGIinHAK0ET7dHIRtogQshcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}