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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25af44d63bbcee2981c6783e8fbf680a8120ba8ea607c5e9d2b34a874e3acb17' 
  AND token = '5pUbTh4GWhbsRNpwsSI83dS5ANg0nMP+NfDZrsbh8TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}