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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85a0cc35d4cc68c630546325cebd4144700cf3d19e5ffccff7b08f4a0c1de850' 
  AND token = 'IKAPVT0GTzUnCQw+dI1pG2/8e/hPrewlnwebpQ7TqL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}