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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665447cad43a48768eb03372c348cc3a35d322ef69fa43ea114a58cf2e82025f' 
  AND token = '+MtC4K9IcYxpVwL2F5jdbBAwWEjuyj91CLhDWFdrWE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}