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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22168eff473ed51da656ebb2c523082e0de5eb2e984ba679703461ddd563561' 
  AND token = 'u7gSB1CXgwf7wanKNx3/uMA6bmPjFAvZ+eox14h/UlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}