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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29c2d6f93d16a8792a0e6fb1be4edcd325d604ad2a53885afb4f46ae1e79b808' 
  AND token = 'VpsDfYUUVPLvEohRrmf3tw6me+SAWDQ2WRDAgM7TY2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}