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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1783277f7f049594f149592554a16d0b54af4b49d91d65736deeba9044ef58f' 
  AND token = 'ikYsJPS1rBOadd1G1aHdzd6HvQ7LlSdwoF1dJbpcfgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}