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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549c37aa02cdcee83a5c6fa1a61a54c0d211b0337ed9c6fcf1175c16292b5fd2' 
  AND token = '/yCVONxKB8bjdT93b8TqWC3+IgJa9yIpHprqlZ7AOdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}