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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb9a95c0c5450c2627e5b090d11f50e46f655ebc73322c125af5d28cdf183c0' 
  AND token = '66FiIzJ6RcSreRzglB8P//OoO0k/RDprgcDxzRs918I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}