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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c165ce25b53680eaf154f567f513d04b9ed521d6e40485603ad5316728429a75' 
  AND token = 'mFaid48fOKyXeRbj/hgG3SQwiw0jtSCD4c2nqDeGIMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}