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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b37b21d294ab36454ae4dea50a1f188a58facbba82f99607904c290339b2b22' 
  AND token = 'oIDfmWvz23x5V1VkdLpFubGfrsuUxKU4sPn5+uXNDTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}