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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43d0e4c6a298154d3d91f27330a156d0ed8d887e133be549eb661b3a70ae176' 
  AND token = 'G11NKj8BmYMP/b56GsJiT+JOmIXc4wfVR6UZ04Z1kHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}