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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d732180d462d6b19bdff398e21f0057bcc874dab4fa7fb99b4872b3dc93187d' 
  AND token = 'CitYx3+ivRvEfjlujyqlR631r3kW2CQllkiHHcQhMuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}