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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5397da4424520798a5a9d674c9c9d2fcebf43bf3ba2f7fbaeeda8dc25d7422a5' 
  AND token = 'Ue/zJLBO2swOi6Zrre7J6qYwrxC4VkEEcUzvrKba0SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}