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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb208b9b0595710fda8debcb0a8d52d4f8e78a4afd96ed65895e8b4c3e9ff65' 
  AND token = 'Qzp/URvaD0LAFw4/0vTG+iSFgM7ugGfrTr9lvd/fAZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}