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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd15000cb60ccf9f4e46f06cadfa36a937ccc55bf8f8afa23c99c190c21957577' 
  AND token = 'kMTWRwxb3z0i2ExqY0e9aZ9+ZWDKKpHZow62nmZ/580=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}