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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '065b0c1d0b6ab106daf804320ee1d6cef5f543f185aa261a1f7db435b7dffb48' 
  AND token = 'iNgp1sm9rZgcFVolfDomHqOmdY+ZG2wh9dhvtuaQupE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}