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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500eafd40fb97b5cf344b511404fd2be1c67d0cdec2f05d81703dde504d52be9' 
  AND token = 'UmKE5UOSLTrA/y0GWOVYTq7jjrKNw1VCvH9/Th8TjRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}