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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54c52678fd79eb01787ae1fa92e45e0f9aab9986860a4bf2fd0bb3e9127d003a' 
  AND token = 'jop4DwKTIj84rgazhxRRRfnFPf2hawHrrBA/w07Dbkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}