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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '701e72577fe859823edc016c7d0af4ea9485d6bcf0c6c58ca00ee83acacc0221' 
  AND token = 'R00ddd4ZS3GCFvCDE79OvHNV/SHymeLO6pD0ZOi3Rog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}