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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc46348a4231cbe6301767ce8478db5acb8f5aecca8dcd79b94691d5df6335c' 
  AND token = 'nhoYc1dbE8hjMPvLjlhOmpTqYTNGlySWkSrwfvG8KY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}