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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781663aed36864d466dfe7d36ca62d0acf55c1e489cb9c34a94c3f8a317c6701' 
  AND token = 'Cm6917Rxgg/mE//9RxDomE97fM6cPaGF3+rhD3rxuL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}