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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '881ca217f45b08cddeb744c21722118157bb9bc3c661b14e8373ebd0dd1b9611' 
  AND token = '43OgDkTKN3HmAiwHWfBOYsHiNAnksFjsPw/mN3l3EEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}