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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b7350540a4076bf07dcc252c3a1d3ea950c5f7b64fcf70a87389304e97c348' 
  AND token = 'hxt4Bsgs+V6tjVP/68bx2TVBo+2Ge+SmLiTdVPpfTEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}