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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c1f64e8487f78cf607825bacd9e9db27de2423f67e764c84d8aa832d823559' 
  AND token = 'v8VCNXIO+Xe47C8112N6nS1GEiGsJgZk6YG/jdRq2MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}