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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8048cf81c18db9fac38840c05c7d8a4d6a424b74556a3b7d61539921df9255b6' 
  AND token = '/ui+G6s4oT6t4V5rkqqlVjoZYeLs0sSqz7fmTssYOl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}