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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c346483971076d7e07bb31aaaa3fc1a35132fca4c052ae8a0d4f30ec288334' 
  AND token = 'z8VAuGYBhPN4FpZBCM7eA7yTwDSjMkh3UfHDgk3+EfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}