SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45dab620fdb3c6c9fd7ea3c4e53d2a2e5129ff9434fc03a8a08003df63e5754f' 
  AND token = '5k5Mp05Ur/AJmcicYOZKvthlihfQQpssxbx8q1oD8Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}