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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f19f8a03687390841f30ddea77b3e06cd8c5261a141a5a77d1f9856934fb448f' 
  AND token = '/U/SbUu5GyyeqT1q+c9yLVDDOXUDpXGuU8tx9Gzx6z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}