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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f0fa807f0bd7b406691a32ccda595b17de64f0dd0adadc9f25f4c2e8d0e815f' 
  AND token = 'F3sBcP/x8z5wpRjrYaVwkk3Lfa14zVMcxhiOZ/skMpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}