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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38745b1298046e7355d7de6cb58cb24d48c63e042bb7d0ac5dd4851dd0a3f53a' 
  AND token = 'ifeXS7BGAsy8oLlJ6vdR5tQh0cnfXXdIxFYPCztMGi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}