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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50380f225f7d6b6dc65285f349c46cafd3bb6a64569ce248c722f375598b4afa' 
  AND token = 'Ou2APEdRryC8uDfK9zCUMpvpEIiiOT1D/JxtswvZn3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}