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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1648be6ad0047fdda6f331f1378663d9054e563bbb68da63b2534e518fdf3699' 
  AND token = 'Macdj6/YVEOPxOc7LDJmXo+zf3MJtTrBS5+MeI3VqxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}