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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '641a64c042115d7e55bc09db98e20eaf9e3a79455ba75ce889b1db547033f3c4' 
  AND token = 'P4PkMUnvck97ld/6hrtqJcd6lgt6Sc2jnOWKh1NiygI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}