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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b65c4824242ac36a836cc67d5a1e308d4f3842a1505aca09888388ef2aac42a' 
  AND token = 'u/mt/x38LiFpc9GD0AZnXaARsxcddn7GKlUOcWi5KpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}