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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77c9c59ea774d0e3a394dfb7b44a35e7aefa2159097f3c2af094f805a24e6b89' 
  AND token = '+VC8qY0Bsk8U17vh1BXlDrpXlf2qnBsEwPRN5EKJ3mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}