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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b78fa7fc492a526451a688f1f3491e7d05f2bc74c8c03331448479f4e7c229d' 
  AND token = 'x2nkHwTJ4tCEAfKsJRwyhX8PU3GbYbcTG0cD3i/8sA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}