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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c90620b62266a16ba8bd1d890a5072f839801fe5a90b6f7c1c62d172f99f4d' 
  AND token = 'pe8esDentyZ9aVykE496OWFRHA1BSim3BbOkXI+NRS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}