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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ca3cde8572cd08b011395864cb76c3a1966b5dba2d56cf5a1e173fa04c59af' 
  AND token = 'a0YumCErLeP3nyytiD94sD98vn8ORNLodDXgH/yqf9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}