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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df25a41d1f15caa984dd36f19fe7226ff25a6d518df0f9e6d00eaa2449d3ad43' 
  AND token = 'A2sEt98SXLrbt6OoOiqehpu4Ylr8OH/egSkR8MwX9Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}