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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaca046a29a0c4cbf45ada3ba91668a6d2974e6124512dc85a73ab430bc63014' 
  AND token = '+ykAS8AbVot1vrVsQdvOt681awSZqbEGhGuGar4jHnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}